Think it might be lice?

Know the signs. Skip the aisle. Get the prescription that works.

The drugstore shelf is not what it used to be. Over 98% of U.S. head lice now resist those products. Here is how to tell if it is lice, and what to do next.

Get Natroba™ Prescribed Now

Prescribed online in minutes. No appointment.

Is it head lice?
Here is what to look for.
Check for these common signs before you treat.

Persistent itching, especially behind the ears and at the nape of the neck.

A tickling feeling of something moving in the hair.

Tiny tan insects about the size of a sesame seed on the scalp.

Skip the pharmacy aisle.

Today, head lice resistance to permethrin-based products found on pharmacy-aisle shelves is over 98% across 48 states. That is why so many treatments fail and lice keep coming back. There is a better first step.

What is Natroba™ (Spinosad)?

A prescription head lice medicine, FDA-approved for adults and children 6 months and older. One 10-minute application, no nit combing required for most patients.

  • Leaf Icon
    Prescription strength

    An effective medicated shampoo, rather than the pharmacy-aisle option.

  • Calendar icon
    Single Application

    One 10-minute application for most patients.

  • Hair Comb icon
    No nit combing required

    Skip the tedious comb-out for most patients.

  • Works when OTCs don’t

    Effective against permethrin-resistant lice.

Product bottles
Lice-free at Day 14

86.7%

Natroba™

vs.

42.9%

Permethrin 1%

In head-to-head clinical studies, Natroba™ was twice as effective as permethrin 1%, the active ingredient in Nix®.
Skip the wait. Get prescribed at home.

Answer a few questions. A quick online eligibility check, about 2 minutes.

See your exact cost. Major insurance plans accepted. You see your copay before you commit.

Same day delivery to your door or pickup at a local pharmacy. A licensed clinician reviews and prescribes.

Ratings circle with star

4.8 / 5 average user rating on WebMD
"We tried Nix three times. We tried RID. Nothing worked. One application of Natroba™ and the lice were gone."

Get Natroba™ now

Or ask your doctor about Natroba™.

References

  1. Gellatly KJ, Krim S,Palenchar DJ, et al. Expansion of the knockdown resistance frequency map for human head lice (phthiraptera: pediculidae) in the United States using quantitative sequencing. Journal of Medical Entomology, 2016:1-7.
  2. Natroba™ (Spinosad) prescribing information. Cipher Pharmaceuticals Inc.
  3. Centers for Disease Control and Prevention. (2024 June 4). About head lice. U.S. Department of Health & Human Services. Retrieved December 19 2025, from https://www.cdc.gov/lice/about/head-lice.html
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